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TitleAn unusual case of anti-myelin oligodendrocyte glycoprotein (MOG) associated optic neuropathy.
PurposeTo report a case of recurrent transient visual loss and delayed onset of optic disc edema related to anti-myelin oligodendrocyte glycoprotein associated optic neuropathy.
MethodsCase report of a 44-year-old male patient with anti-MOG associated optic neuropathy.
ResultsWe report a case of a 44-year-old patient referred with a history of recurrent intermittent transient visual loss of his left eye, followed by persistent visual loss of the right eye two weeks later. Unilateral optic disc edema of the right eye only appeared two weeks after visual loss. A complete neurological and cardiovascular work-up elsewhere remained unremarkable. Additional laboratory tests revealed the presence of anti-MOG antibodies and a positive IGRA-test. Treatment with steroids (while covering for the positive IGRA-test) was able to restore useful vision in his right eye and the left eye did not suffer from further episodes of visual loss.
ConclusionAnti-MOG associated optic neuropathy should be considered in case of dense visual field loss, along with neuromyelitis optica (NMO). Usually anti-MOG is associated with optic disc edema, whereas NMO is not. This case teaches us that optic disc edema may take some time before manifesting. Transient visual loss might be part of the symptoms, as it did not recur after treatment. It also illustrates the importance of assessing the presence of tuberculosis before starting high doses of steroids.
Conflict of interestNo
Authors 1
Last nameMEYERS
InitialsM
DepartmentAntwerp University Hospital, Department of Ophthalmology
CityAntwerp
Authors 2
Last nameVAN LINT
InitialsM
DepartmentAntwerp University Hospital, Department of Ophthalmology
CityAntwerp
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