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Presentation typeE-poster
TitleMicrospherophakia and lens subluxation in Klinefelter syndrome: a case report
PurposeThe aim of this article is to emphasize the importance of a proper general health assessment and systemic disorders in the case of cataracts surgery in younger patients without the notification of prior trauma.
MethodsThe presented case report concerns a 52 year old male that was referred to the University Hospitals Leuven for phacoemulsification under general anesthesia. A brief review of literature was performed.
ResultsPre-operative assessment revealed a cortico-nuclear cataract in both eyes, with dislocation of the lens in the left eye presumably caused by zonular dehiscence without history of blunt trauma to the head or eye. However, patient’s history revealed the coexistence of Klinefelter syndrome (47, XXY), a sex chromosome aneuploidy causing primary hypogonadism with a variable phenotype severity (taller, smaller testicles, late puberty onset etc.) Literature study reported a single case with microphakia in a Klinefelter patient. Intraoperatively a more cautious approached was withheld and a capsular tension ring was used to strengthen and divide forces exerted on the capsular bag. Post-operative outcome was successful with good visual outcome and no interoperative complications.
ConclusionIn conclusion this case report stresses the importance of proper preoperative assessment in early-onset cataract. Especially general medical history and enquiry of systemic disorders such as connective tissue diseases (Marfan, Ehlers-Danlos, Weill Marchesani Syndrome etc.) and metabolism disorders like homocystinuria.
Conflict of interestNo
Authors 1
Last nameLEYSEN
Authors 2
Last nameVan Keer
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