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TitleNested Variant of Urothelial Carcinoma of the Bladder Metastatic to the Choroid.
Abstract Nr.P11
PurposeTo report the first reported case of choroidal metastasis from the nested variant
of urothelial carcinoma of the bladder.
MethodsA 58-year-old man developed a progressive painless blurred vision in the right
eye. Fundus examination revealed a minimally dome-shaped choroidal lesion simulating a
melanoma. Eight years earlier, he was diagnosed with transitional cell carcinoma of the
bladder trated with cystoprostatectomy and chemotherapy. A systemic workup did not reveal concomitant metastatic disease. Fine needle aspiration biopsy was not contributory to the diagnosis.
ResultsAs per patients’s choice, enucleation of the affected eye was performed.
Histopathological examination confirmed the diagnosis of choroidal metastasis from nested
variant of urothelial carcinoma of the bladder. The patient was diagnosed 4 months later with systemic metastatic disease and died 7 months after the ocular diagnosis.
ConclusionChoroidal metastasis from bladder carcinoma is an extreme rare event with
a poor survival prognosis.
Author 1
Last nameLEVECQ
InitialsL
DepartmentCliniques St-Luc, UCL
CityBruxelles
Author 2
Last nameDE POTTER
InitialsP
DepartmentCliniques St-Luc, UCL
CityBruxelles
Author 3
Last nameGODFRAIND
InitialsC
DepartmentCliniques St-Luc, UCL
CityBruxelles
Author 4
Last nameGUAGNINI
InitialsA-P
DepartmentCliniques St-Luc, UCL
CityBruxelles
Author 5
Last nameKOZYREFF
InitialsA
DepartmentCliniques St-Luc, UCL
CityBruxelles
Author 6
Last nameMICHIELS
InitialsX
DepartmentCentre Hospitalier
CityMouscron
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