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This abstract is assigned to session BOG-SBO: Glaucoma / Glaucome

Title	Correlation between Ocular Pulse Amplitude and Visual Field Defects
Abstract Nr.	172

Purpose	To investigate the correlation between the Ocular Pulse Amplitude (OPA) measured by Pascal Dynamic Contour Tonometer (DCT) and visual field defects in patients with Primary Open-Angle Glaucoma (POAG), Ocular Hypertension (OHT), and in Glaucoma Suspects (GS).
Methods	Hundred eyes of 52 patients were examined. OPA was measured with DCT by one investigator masked to the visual field data. Only measurements of quality q1 and q2 were included. Unreliable visual fields (n=3), other diseases capable of causing visual field loss (n=3) and visual fields taken more than 3 months before or after OPA measurement (n=10) were excluded. Visual fields were performed by Humphrey (n=52) or Octopus (n=32), and were analysed with Peridata software. Mean defect (MD), pattern standard deviation (PSD; square root of LV), and regression analysis of MD and PSD (square root of LV ) (Trend indices) were correlated to OPA for each eye. Spearman correlation coefficients were used to assess the correlation.
Results	Fifty-three eyes had POAG, 14 had OHT, and 17 were GS. The mean follow-up was 46 (6-96) months. There was a statistically significant correlation, both for Humphrey (n=52) and Octopus (n=32), between OPA and MD (respectively rs = 0,681 and rs = 0,670, p<0,001), and between OPA and PSD (square root of LV) (respectively rs = -0,463 and rs = -0,629, p<0,001). There was a weak, but statistically significant correlation between OPA and the regression analysis of MD (rs =0;250, p=0,05).
Conclusion	A small ocular pulse amplitude might be a risk factor for the development and progression of glaucomatous visual field defects.

Author 1

Last name	VULSTEKE
Initials	C
Department	AZ Middelheim
City	Antwerpen

Author 2

Last name	STALMANS
Initials	I
Department	KULeuven
City	Leuven

Author 3

Last name	RENIER
Initials	C
Department	KULeuven
City	Leuven

Author 4

Last name	ZEYEN
Initials	T
Department	KULeuven
City	Leuven