|Title||Analysis of a particular kind of central serous chorioretinopathy characterised by a leopard-spot pattern aspect in transplanted patients on long-term steroid treatment|
|Purpose||The purpose of our study is to analyse the rate of appearance of a leopard-spot pattern in transplanted patients with steroid-induced central serous chorioretinopathy (CSC) and to analyze this pattern with multimodal imaging.
|Methods||We carried out a prospective, monocentric and interventional study on patients with heart, lung or kidney transplant and who have been treated with corticosteroid for at least 3 years. Best corrected visual acuity (BCVA), color fundus photographs, fundus autofluorescence (FAF), spectral domain optical coherence tomography (SD-OCT) and a measure of subfoveal choroidal thickness were performed. If CSC was suspected, an additional fluorescein (FA) and indocyanine green angiography (ICGA) was performed.|
|Results||Among the 53 patients included in this study, four patients were diagnosed with CSC. Three had a “classic” form of CSC and only one showed a leopard-spot pattern.
We then associated this case with three other patients who have been previously diagnosed with chronic CSC and who showed the same kind of pattern. All cases showed a peculiar leopard-spot appearance on FAF and FA. In contrast to typical CSC, these cases did not demonstrate the typical features of hyperpermeability on ICGA and had normal choroidal thickness.
|Conclusion||Given the fact that the management and prognosis of CSC are totally different from those of an intra-ocular lymphoma, it is fundamental that chronic CSC is recognized as a new differential diagnosis of “leopard-spot pattern” observed on fundoscopy.|
|Conflict of interest||No|
|Last name||VAN BOL|