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This abstract is assigned to session AOB FP

Title

Optical coherence tomography angiography suggests size of the foveal avascular zone to be associated with physical fitness

Purpose	To evaluate if individual physical fitness affects optical coherence tomography angiography (OCTA) measurements of ocular perfusion.
Methods	Sixty-five healthy participants (age 21.7 ± 2.2 years) performed a standardized incremental continuous running test to determine their physical fitness defined as (I) individual anaerobic threshold (IAT, running speed at baseline blood lactate + 1.5 mmol/l) and (II) maximal exercise capacity (maximal running speed, Vmax). Foveal avascular zone size (FAZ) and macular full-thickness flow density (FDM) were evaluated using OCTA, as was FD in the radial peripapillary capillary layer of the peripapillary region (FDrPP), and decorrelation signal index in the choriocapillaris (CCDI).
Results	An inverse correlation between Vmax and FAZ (r = -0.297, p = 0.018) was detected. FDM, FDrPP and CCDI did not show any correlations with physical fitness parameters.
Conclusion	OCTA FAZ measurements are associated with individual physical fitness in young healthy adults.
Conflict of interest	No

Authors 1

Last name	NELIS
Initials	P
Department	UKM, UZB (VUB)
City	Muenster, Brussels

Authors 2

Last name	Schmitz
Initials	B
Department	UKM
City	Muenster

Authors 3

Last name	Alnawaiseh
Initials	M
Department	UKM
City	Muenster

Authors 4

Last name	Müller
Initials	V
Department	UKM
City	Muenster

Authors 5

Last name	Mihailovic
Initials	N
Department	UKM
City	Muenster

Authors 6

Last name	Ten Tusscher
Initials	M
Department	UZB (VUB)
City	Brussels

Authors 7

Last name	Alten
Initials	F
Department	UKM
City	Muenster